In the Aeon Client, open a request and modify a text field so that it is highlighted yellow to indicate pending changes.
Routing the request (both request status routing and photodup routing) or selecting a next step (other than Cancel) will immediately perform that action without prompting to save changes. The route options may prompt you to confirm that you want to route if you haven't checked the "Don't show this again" checkbox, but you won't be prompted to save pending changes.